Biochemical testing of the thyroid: TSH is the best and, oftentimes, only test needed - A review for primary care. For example, a BUN level of 75 mg/dL is highly considered alarming. If your BUN test shows extreme results, it might signal kidney failure. The association between subclinical hypothyroidism and sleep quality: A population-based study. A level surpassing the BUN normal range of 6-20 mg/dL indicates kidney problems. Effect of high-dose biotin on thyroid function tests: Case report and literature review. Reviewed May 2017.Īrdabilygazir A, Afshariyamchlou S, Mir D, Sachmechi I. National Institute of Diabetes and Digestive and Kidney Diseases. Does fasting or postprandial state affect thyroid function testing? Indian J Endocrinol Metab. Nair R, Mahadevan S, Muralidharan RS, Madhavan S. A blood urea nitrogen (BUN) or urea test measures the amount of nitrogen in your blood that comes from the waste product urea. Interferences with thyroid function immunoassays: Clinical implications and detection algorithm. Pitfalls in the measurement and interpretation of thyroid function tests. Koulouri O, Moran C, Halsall D, Chatterjee K, Gurnell M. 2016 American Thyroid Association guidelines for diagnosis and management of hyperthyroidism and other causes of thyrotoxicosis. Comorbidities, concomitant medications, and diet as factors affecting levothyroxine therapy: results of the CONTROL Surveillance Project. Thyroid and pregnancy: Thyroid status and risk of miscarriage.Ĭhaker L.

Evaluation of pregnancy and thyroid function. Gender-specific regulation of response to thyroid hormone in aging. Suzuki S, Nishio SI, Takeda T, Komatsu M. Note that BUN values remain within the normal range until more than 50 of renal function is lost. Elevated BUN is also associated with increased stroke risk in heart surgery, and adverse outcomes in atherosclerosis and heart failure patients 20, 21, 22. Normal TSH reference range: What has changed in the last decade? JCEM. High BUN is associated with increased mortality in critically ill patients 6, 17, 18, 19.

Seasonal variations in levels of human thyroid-stimulating hormone and thyroid hormones: a meta-analysis.

Kuzmenko NV, Tsyrlin VA, Pliss MG, Galagudza MM.

TSH reference ranges should be used to safely guide thyroid hormone treatment in hypothyroid patients. The test is frequently requested along with the serum creatinine test since simultaneous determination of these 2 compounds appears to aid in the differential diagnosis of prerenal, renal and postrenal hyperuremia.American Thyroid Association. The determination of serum BUN currently is the most widely used screening test for the evaluation of kidney function. Increased blood urea nitrogen (BUN) may be due to prerenal causes (cardiac decompensation, water depletion due to decreased intake and excessive loss, increased protein catabolism, and high protein diet), renal causes (acute glomerulonephritis, chronic nephritis, polycystic kidney disease, nephrosclerosis, and tubular necrosis), and postrenal causes (eg, all types of obstruction of the urinary tract, such as stones, enlarged prostate gland, tumors). This is the most important catabolic pathway for eliminating excess nitrogen in the human body. The ammonia formed in this process is synthesized to urea in the liver. In protein catabolism, the proteins are broken down to amino acids and deaminated. Diabetes Management Blood urea nitrogen (BUN) is a blood test performed as a marker of kidney function. Urea is the final degradation product of protein and amino acid metabolism.

Bun test results normal range